10 Best Bed Bugs Repellents 2025 in the United States

Ortho Home Defense Max Bed Bug, Flea and Tick Killer is an effective spray for tackling bed bugs, including pyrethroid-resistant ones, along with bed bug eggs, fleas, and ticks. The spray formulation comes with a Comfort Wand that allows precise application, making it easier to reach tight spots like mattress seams and baseboards where bed bugs often hide. This feature enhances ease of use, especially for treating specific areas indoors.

The product is part of a comprehensive system for bed bug control, suggesting it works best when combined with other Ortho products for detection and treatment in cracks and crevices. One gallon volume is suitable for multiple treatments or larger areas, and it is a popular choice in the market. While the spray formulation is convenient, it can be cumbersome for some users due to the weight of the container. Frequent applications may be necessary for maintaining long-term efficacy.

In terms of safety, users should follow guidelines carefully to avoid any potential toxicity, particularly in spaces occupied by pets and children. Some users may find the scent strong, which could be a downside for those sensitive to odors. For those dealing with bed bug infestations, this product offers a practical and effective solution.

The EcoRaider Bed Bug Killer Spray is a non-toxic, eco-friendly solution designed to effectively combat bed bugs. Its active ingredients are naturally derived, making it safe for use around children and pets, and it can be applied directly to mattresses and box springs. This formulation has been proven to kill bed bugs at all life stages, including those resistant to traditional pesticides, according to studies published in reputable journals and field tests.

This makes it a robust option for those looking to eradicate bed bugs in sensitive environments like public housing or households with vulnerable individuals. The product boasts an extended residual effect, continuing to protect against bed bugs for up to two weeks after application, which can provide peace of mind for users dealing with infestations. However, at 8 pounds and with a large volume of 128 fluid ounces, it may be cumbersome for some users to handle and store.

Additionally, while the product is designed to be safe and non-toxic, some users might find the oil-based formulation less convenient if they prefer a quicker-drying solution. For those seeking a powerful, natural bed bug killer with extended protection, the EcoRaider Bed Bug Killer Spray offers a compelling option, provided they are comfortable with its size and oil-based form.

The Hot Shot Ready-to-Use Bed Bug Killer Spray is designed to kill bed bugs and their eggs, as well as fleas and dust mites, making it a versatile insecticide for indoor use. It uses a water-based formula which means it won’t stain surfaces and importantly, it leaves no odor, which is a big plus for indoor use where lingering smells can be unpleasant. The spray is easy to apply by targeting common hiding spots like mattress seams and creases, but it’s important not to soak these areas—just dampen them.

This product is meant to be used as part of a larger treatment plan, with reapplications every two weeks while bed bugs are present, indicating it doesn’t provide a long-lasting residual effect on its own. Regarding safety, it’s not intended for use on pets, so care is needed when applying around animals.

This spray is suitable for people looking for an easy-to-use, no-odor bed bug treatment that can be integrated into a broader pest control routine. However, those needing a one-time, long-lasting solution might find the need for repeated treatments inconvenient.