10 Best Allergy Mattress Covers 2025 in the United States

The SafeRest CloudGuard Twin XL Mattress Protector is designed to offer an ultra-comfortable sleeping experience with its plush and fluffy quilted pillow top. As an allergy-mattress cover, it performs impressively with its allergen barrier, thanks to the thick padding that helps block dust mites and other allergens. The material used, CloudGuard (Ultra Padded), ensures a luxurious feel while maintaining a breathable environment, which is crucial for a comfortable sleep.

One of the significant strengths of this product is its 100% waterproof membrane, which safeguards the mattress against fluids, urine, and perspiration, keeping it dry and clean. This feature is particularly beneficial for households with children or pets. The mattress protector is machine washable, making it easy to clean and maintain, a convenience for busy users. In terms of fit, the Twin XL size with dimensions of 80 x 39 x 14 inches and a pull-on closure type ensures a snug fit on most Twin XL mattresses. The noiseless feature of the fabric further enhances the sleeping experience by eliminating any crinkling sounds common in other mattress protectors.

However, there are a few considerations to keep in mind. The product’s thickness and plush nature might make it less breathable compared to thinner mattress covers, which could be a drawback for those who tend to sleep hot. Additionally, although it claims to be noiseless, individual experiences may vary, and some users might still notice slight noise upon movement. Despite these minor drawbacks, the SafeRest CloudGuard stands out as a high-quality choice for those seeking a combination of comfort and protection in their mattress cover, particularly beneficial for allergy sufferers and families.

The SafeRest Waterproof King Size Mattress Protector is designed to protect your mattress from fluids like sweat, spills, and urine, making it a strong choice if you want to keep your bed clean and allergen-free. It’s made mostly of cotton (80%) with some polyester, which helps it feel soft and breathable, so you’re less likely to feel hot during the night. The waterproof layer is effective without being noisy, which means it won’t disrupt your sleep with crinkly sounds—a common issue with some mattress covers.

The fitted design with stretchable pockets ensures a snug fit on king-size mattresses, so it won’t shift around easily. This protector is also easy to care for since it’s machine washable and can be tumble dried, making maintenance simple.

This mattress protector performs well in keeping your mattress dry, comfortable, and quiet, especially if you want a hassle-free, breathable cover.

The PlushDeluxe Premium Bamboo Mattress Protector is a strong contender in the allergy mattress cover category, particularly for those who prioritize comfort and protection. One of its key strengths is its hypoallergenic properties, making it ideal for allergy sufferers and anyone looking to reduce allergens in their sleeping environment. The use of natural bamboo fabric not only provides a soft feel but also promotes breathability, ensuring a cool and comfortable sleep. Its waterproof feature is impressive, effectively resisting fluids from spills or bodily accidents, which can be particularly beneficial for families with young children or pets.

In terms of fit, the protector is designed to accommodate a variety of mattress types and depths, going up to 18 inches, which adds versatility. Plus, it remains noiseless, a bonus for those who are sensitive to sounds while sleeping. The ease of cleaning is another highlight, as it's washable and maintains its quality over time.

Some potential drawbacks should be noted. While the bamboo material is generally durable, it may not be as robust as some synthetic options on the market, which could affect longevity. Additionally, although the protector is marketed as waterproof, it may not offer the same level of protection as thicker, more traditional waterproof covers. Lastly, while the white color looks clean, it may show stains more readily than darker options, potentially requiring more frequent washes to maintain its appearance.